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Air Toxicology and Epidemiology

Technical Support Document for Describing Available Cancer Potency Factors
[05/31/05]

The Technical Support Document for Describing Available Cancer Potency Factors (TSD) contains cancer unit risks and potency factors for 122 of the 201 carcinogenic substances or groups of substances for which emissions must be quantified in the Air Toxics Hot Spots program. The purpose of this document is to provide a summary of the data supporting the carcinogenic potential of the substance or group of substances and to provide the calculation procedure used to derive the estimated unit risk and cancer potency factors.

This document has been revised from the December 2002 version. The substantive changes from the earlier version are 1) the adoption of the of the Toxicity Equivalency Factor scheme (TEF WHO-97 ) developed by the World Health Organization/European Center for Environmental Health (WHO-ECEH) for determining cancer unit risk and potency values for polychlorinated dibenzo- p- dioxins and dibenzofurans and for polychlorinated biphenyls (PCBs) where PCB congener data is available, and 2) the addition of a cancer unit risk factor and supporting chemical summary data for naphthalene. Both the adoption of the TEF WHO-97 scheme and the cancer unit risk for naphthalene underwent public and peer review, and were approved by the Scientific Review Panel (SRP) of the Air Resources Board (ARB). The document formatting has also been changed slightly. The Unit Risk and Cancer Potency Values table has been moved into Appendix A, Chemical-Specific Information Summaries into Appendix B, and all other Appendices have been renumbered appropriately.

Follow this link to download the May 2005 Technical Support Document for Describing Available Cancer Potency Factors

 
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